
Product Name: Mouse Anti-Human CD45 |
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Product Number: PDZMM107 |
Clonality: Monoclonal |
Conjugation: Unconjugated |
Host Species: Mouse |
Target Species: Human |
Mouse Anti-Human CD45
- Background
- Product Details
- Storage & Handling
- Applications
The CD45 antigen (PTPRC) is a type I transmembrane protein involved in regulating immune cell signaling, specifically T- and B-cell receptor signaling. It is expressed on all differentiated hematopoietic cells, except erythrocytes and plasma cells. CD45 is critical for immune cell activation and function, and its expression and isoform variations are important in the regulation of immune responses. CD45 functions by activating Src family kinases necessary for antigen receptor signaling or suppressing JAK kinases to regulate cytokine receptor signaling.
Properties
- Form: Liquid
- Storage Instructions:
- Shipped at 4 °C.
- Store at -20 °C. Avoid freeze/thaw cycle.
- Storage Buffer:
- Phosphate-buffered saline (pH 7.4), contains stabilizer and ≤0.09% sodium azide.
- Purity: SpG purified
- Purification Notes: Prepared by immunoaffinity chromatography using Protein G.
- Conjugation Notes: Unconjugated
- Clonality: Monoclonal
- Isotype: IgG
General Notes
- For extended storage, aliquot contents and freeze at -20 °C or below.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use.
- Customer feedback indicates positive results with this antibody. If the antibody fails to perform as expected, please contact our scientific support team for assistance.
Product Usage Information
- For Research Use Only: Not for diagnostic procedures.
Tested Applications:
- Western Blotting: 3-5 µg/mL
- Immunohistochemistry (Paraffin): 5-10 µg/mL
- Immunohistochemistry (Frozen): 5-10 µg/mL
- Immunofluorescence: 5-10 µg/mL
- Flow Cytometry: 5-10 µg/mL
Application Notes:
- Optimal dilution/concentration should be determined by the end-user based on experimental conditions.
Overview
Mouse Anti-Human CD45 is a monoclonal antibody targeting the CD45 protein, also known as PTPRC (protein tyrosine phosphatase, receptor type C), a receptor-type tyrosine phosphatase involved in regulating T- and B-cell receptor signaling. This antibody is prepared using a KLH-conjugated synthetic peptide derived from the human CD45 protein for immunization. It is suitable for applications such as Western Blotting (WB), Immunohistochemistry (Paraffin & Frozen), ELISA, and Immunomicroscopy.
- Published Studies: We will update this section with studies where this antibody was successfully used. (“This antibody was featured in Journal XYZ, 2023, in studies on targeted immunotherapy.”)
References
This product was originally developed at Avicenna Research Institute, Tehran, Iran, and assigned to PADZA Company under contract 98/15/191, dated 98/01/10.
(You can view the article referenced in the NCBI: PMC4137948)
- Case Studies: Brief summaries of key research projects or notable outcomes demonstrating the product’s effectiveness.
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Publications & Research
Ordering Information
Sizes and Packaging Options: Various sizes (50 µL, 100 µL) and larger quantities are available.
Sizes | Ordering Code | Packaging | Availability |
50 µL | PDZMM101-50 | Standard vial | Order Now |
100 µL | PDZMM101-100 | Standard vial | Order Now |
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PADZA ensures product performance when purchased directly from PADZA or authorized distributors. Contact our scientific support team for any technical issues.
📩 Contact our Scientific Support Team for application-specific queries or troubleshooting.
Terms & Conditions: This product is guaranteed only when purchased directly from PADZA or its authorized distributors.
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At Padza, we are committed to providing exceptional support for our products and services. Whether you have feedback, need assistance with an application, or require technical troubleshooting, our team is here to help. Please fill out the form below to get in touch with us, and our technical experts will respond promptly to assist with your specific needs. We look forward to supporting your research and ensuring the success of your projects.
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