Product Name: Mouse Anti-Human EVA1 |
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Product Number: PDZMM134 |
Clonality: Monoclonal |
Conjugation: Unconjugated |
Host Species: Mouse |
Target Species: Human |
Mouse Anti-Human EVA1
- Background
- Product Details
- Storage & Handling
- Applications
Epithelial V-like antigen 1 (EVA1) is a protein whose expression is upregulated in hepatocellular carcinoma (HCC), and it is associated with poor prognosis and recurrence in HCC patients. Overexpression of EVA1 promotes various processes critical to cancer progression, including cell growth, invasion, and migration in vitro. Moreover, EVA1 has the ability to upregulate genes in the ERBB3-PI3K pathway, which is critical for cell survival, differentiation, and migration. These properties make EVA1 an important target for cancer research, particularly in liver cancer studies.
- Host Species: Mouse
- Target Species: Human
- Conjugation: Unconjugated
- Clonality: Monoclonal
- Isotype: IgG
- Form: Liquid
Purification
This antibody is purified via immunoaffinity chromatography, using an immunogen peptide derived from the EVA1protein, coupled to Sepharose 4B.
- Storage Instructions: Store at -20°C upon receipt. Avoid repeated freeze-thaw cycles. The product is stable for several weeks at 4°C as an undiluted liquid.
- Storage Buffer: Phosphate buffered saline (pH 7.4) with stabilizer and ≤0.09% sodium azide.
For extended storage, aliquot and store at -20°C or below. Centrifuge if product is not completely clear after standing at room temperature.
This antibody is suitable for the following research applications:
- Western Blotting (WB)
- Immunohistochemistry (IHC-P, IHC-Frozen)
- Dot Blot
- Immunomicroscopy
- Immunofluorescence (IF)
- Flow Cytometry (FCM)
Recommended starting dilutions:
- Western Blotting: 3-5 µg/ml
- IHC (Paraffin/Frozen): 5-10 µg/ml
- Immunofluorescence: 5-10 µg/ml
- Flow Cytometry: 5-10 µg/ml
Note: Optimal dilutions should be determined by the end-user based on experimental conditions.
Overview
The Mouse Anti-Human EVA1 (Epithelial V-like Antigen 1) antibody targets EVA1, a protein whose expression is notably increased in hepatocellular carcinoma (HCC) and correlates with poor prognosis and recurrence in HCC patients. EVA1 has been found to promote cell growth, invasion, and migration in vitro, suggesting its role in tumor progression. Moreover, it has been shown to upregulate genes in the ERBB3-PI3K pathway, which plays a significant role in cell survival and proliferation.
- Published Studies: We will update this section with studies where this antibody was successfully used. (“This antibody was featured in Journal XYZ, 2023, in studies on targeted immunotherapy.”)
References
This product was originally developed at the Avicenna Research Institute, Tehran, Iran, and transferred to PADZACompany as per contract 98/15/191 dated 98/01/10.
(You can view the article referenced in the NCBI: PMC4137948)
- Case Studies: Brief summaries of key research projects or notable outcomes demonstrating the product’s effectiveness.
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Publications & Research
Ordering Information
Sizes and Packaging Options: Various sizes (50 µL, 100 µL) and larger quantities are available.
Sizes | Ordering Code | Packaging | Availability |
50 µL | PDZMM101-50 | Standard vial | Order Now |
100 µL | PDZMM101-100 | Standard vial | Order Now |
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PADZA ensures product performance when purchased directly from PADZA or authorized distributors. Contact our scientific support team for any technical issues.
📩 Contact our Scientific Support Team for application-specific queries or troubleshooting.
Terms & Conditions: This product is guaranteed only when purchased directly from PADZA or its authorized distributors.
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